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The project began in February 2012

The goal: investigation of CIMP (CpG methylator phenotype) in Colon Cancer using 450k Illumina Human Methylation arrays

Project team: Vitalina Komashko, Justin Guinney, Jonathan Derry

Table of contents:

  1. Project proposal
  2. Literature
    1. MINT markers
  3. Platform
    1. IlluminaHumanMethylation450k.db Bioconductor package
  4. Clinical information
    1. Correlation with technical variables (processing batch/slide)
    2. Clinical variables of interest
  5. DNA methylation
    1. Reading raw data files (.idat)
    2. Relationship between various types of batches in the data
    3. Normalization
  6. more


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