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Synapse Infrastructure

Synapse.org is hosted in Amazon Web Service (AWS) in the US-EAST-1 (aka the Standard) region.

www.synapse.org is the web-based user interface for users to manage data, projects, profiles and teams,

repo-prod.prod.sagebase.org is the endpoint for Synapse Programmatic Clients.


Synapse IP Addresses

This table lists the IP addresses Synapse.org uses. These IP addresses are dedicated and granted to Synapse by AWS. Your IT department may need to add these IP addresses to an “allow list” to allow you to connect to Synapse. Make sure to include ALL addresses.

Host Name

IP Address

Host Name

IP Address

www.synapse.org (web UI)

34.234.4.162

34.233.95.87

54.166.5.127

54.226.68.127

3.215.225.38

44.194.89.171

repo-prod.prod.sagebase.org (endpoint for programmatic clients)

52.45.221.235

52.7.75.49

3.234.175.106

3.88.97.84

44.194.236.113

54.205.219.117