Genotypes
These are the variables describing the mice in the Individual Metadata file. The modelSystemName is used as file annotation. The AD Model Explorer uses the LOAD definition.
Variable | Definition | Example |
officialName | Full name indicating all transgenes, taken from the strain’s JAX datasheet | B6.Cg-Apoetm1.1(APOE*4)Adiuj Abca7em2Adiuj Trem2em1Adiuj/J |
modelSystemName | Strain annotation - see AMP-AD Metadata Dictionary. Used as file annotation | Abca7A1527GAPOE4Trem2R47H |
stockNumber | The JAX stock number | 030283 |
genotypeBackground | Background genotype | C57BL6J |
genotype | Genotype of animal that indicates littermate carriers vs noncarriers | APOE4_homozygous; TREM2R47H_homozygous; ABCA7KI_NONCARRIER APOE4_homozygous; TREM2R47H_homozygous; ABCA7KI_HOMOZYGOUS |
individualCommonGenotype | Genotype of animal that includes LOAD1 or LOAD2 terminology. This is the model name used in the AD Model Explorer LOAD1= APOE4_HOMOZYGOUS; TREM2R47H_HOMOZYGOUS. LOAD2=APOE4_HOMOZYGOUS; TREM2R47H_HOMOZYGOUS; ABETA_HOMOZYGOUS | LOAD1 LOAD1.ABCA7A1527 |
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