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The project began in February 2012
The goal: investigation of CIMP (CpG methylator phenotype) in Colon Cancer using 450k Illumina Human Methylation arrays
Project team: Vitalina Komashko, Justin Guinney, Jonathan Derry
Table of contents:
- Project proposal
- Literature
- MINT markers
- Platform
- IlluminaHumanMethylation450k.db Bioconductor package
- Clinical information
- Correlation with technical variables (processing batch/slide)
- Clinical variables of interest
- DNA methylation
- Reading raw data files (.idat)
- Relationship between various types of batches in the data
- Normalization
- more