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Mouse Naming Standards

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These variables describe the mice in the Individual Metadata file.

Variable

Definition

Example

genotype

Genotype of animal that indicates littermate carriers vs noncarriers.

Format based on Climb variables: <gene>-<allele>_<genotype_symbol>

Complete list of genotype values

  • APOE4-KI_heterozygous

  • APOE4-KI_homozygous

  • APOE4-KI_WT

  • 3xTg-AD_carrier

  • 3xTg-AD_noncarrier

officialName

Full name indicating all transgenes, taken from the strain’s JAX datasheet

  • B6.Cg-Apoetm1.1(APOE*4)Adiuj

  • Abca7em2Adiuj Trem2em1Adiuj/J

modelSystemName

Strain annotation - see AMP-AD Metadata Dictionary. Used as file annotation

Abca7A1527GAPOE4Trem2R47H

See data query

stockNumber

The JAX stock number

030283

genotypeBackground

Background genotype

C57BL6J

individualCommonGenotype

Genotype of animal with LOAD

terminology (used by MODEL-AD Explorer)

LOAD1:

  • APOE4_homozygous

  • TREM2R47H_homozygous

LOAD2:

  • APOE4_homozygous

  • TREM2R47H_homozygous

  • ABETA_homozygous

  • 5XFAD

  • APOE4

  • C57BL6J

  • LOAD1

  • LOAD1.ABCA7A1527G

  • LOAD1.CEACAM1KO

  • LOAD1.CR1long

  • LOAD1.Clasp2L163P

  • LOAD1.Il1rapExon2KO

  • LOAD1.MthfrC677T

  • LOAD1.Plcg2M28L

  • LOAD1.Snx1D465N

  • LOAD2

  • Trem2R47H

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