Versions Compared

Old Version 23

changes.mady.by.user Rich Yaxley (Unlicensed)

Saved on

compared with

New Version Current

changes.mady.by.user Rich Yaxley (Unlicensed)

Saved on

Key

  • This line was added.
  • This line was removed.
  • Formatting was changed.

...

Variable

Definition

Value

genotype

Genotype of animal that indicates littermate carriers vs noncarriers.

Names derived from joining three Climb variables in this specific format:

gene-allele_genotype

Expand
titleGenotype Controlled MODEL-AD-approved Values

3xTg-AD_carrier
3xTg-AD_noncarrier
5XFAD_carrier
5XFAD_noncarrier
Abca7-KI_heterozygous
Abca7-KI_homozygous
Abca7-KI_WT
Abca7-KO_heterozygous
Abca7-KO_homozygous
Abca7-KO_WT
Abca7-V1599M_heterozygous
Abca7-V1599M_homozygous
Abca7-V1599M_WT
Abi3-S209F_heterozygous
Abi3-S209F_homozygous
Abi3-S209F_WT
APOE2-KI_heterozygous
APOE2-KI_homozygous
APOE2-KI_WT
APOE3-KI_heterozygous
APOE3-KI_homozygous
APOE3-KI_WT
APOE4-KI_heterozygous
APOE4-KI_homozygous
APOE4-KI_WT
APP 3&5_carrier
APP 3&5_noncarrier
APPswe_carrier
APPswe_noncarrier
B2M-KO_heterozygous
B2M-KO_homozygous
B2M-KO_WT
Bin1-FLX_heterozygous
Bin1-FLX_homozygous
Bin1-FLX_WT
Bin1-K358R_heterozygous
Bin1-K358R_homozygous
Bin1-K358R_WT
Bin1-KI_heterozygous
Bin1-KI_homozygous
Bin1-KI_WT
Bin1-KO_heterozygous
Bin1-KO_homozygous
Bin1-KO_WT
C3-KO_heterozygous
C3-KO_homozygous
C3-KO_WT
C5-D2_heterozygous
C5-D2_homozygous
C5-D2_WT
C5-KO_heterozygous
C5-KO_homozygous
C5-KO_WT
Cd2ap-KI_heterozygous
Cd2ap-KI_homozygous
Cd2ap-KI_WT
Cd2ap-KO_heterozygous
Cd2ap-KO_homozygous
Cd2ap-KO_WT
Ceacam1-KO_heterozygous
Ceacam1-KO_homozygous
Ceacam1-KO_WT
Clasp2-KI_heterozygous
Clasp2-KI_homozygous
Clasp2-KI_WT
Clasp2-KO_heterozygous
Clasp2-KO_homozygous
Clasp2-KO_WT
Clu-KO_heterozygous
Clu-KO_homozygous
Clu-KO_WT
Clu-rs2279590_KI_heterozygous
Clu-rs2279590_KI_homozygous
Clu-rs2279590_KI_WT
Clu-rs9331888_heterozygous
Clu-rs9331888_homozygous
Clu-rs9331888_WT
Clu-rs9331888nr_heterozygous
Clu-rs9331888nr_homozygous
Clu-rs9331888nr_WT
CR1-KO_heterozygous
CR1-KO_homozygous
CR1-KO_WT
CR1-long_heterozygous
CR1-long_homozygous
CR1-long_WT
CR1-short_heterozygous
CR1-short_homozygous
CR1-short_WT
CR2CR1_heterozygous
CR2CR1_homozygous
CR2CR1_WT
Cx3cr1_heterozygous
Cx3cr1_homozygous
Cx3cr1_WT
Cx3cr1-GFP_heterozygous
Cx3cr1-GFP_homozygous
Cx3cr1-GFP_WT
D2Mit367-D2_heterozygous
D2Mit367-D2_homozygous
D2Mit367-D2_WT
d4MIT251-D2_heterozygous
d4MIT251-D2_homozygous
d4MIT251-D2_WT
Dlx6a-Cre_heterozygous
Dlx6a-Cre_homozygous
Dlx6a-Cre_WT
Edn2-FLX_heterozygous
Edn2-FLX_homozygous
Edn2-FLX_WT
Edn2-KO_heterozygous
Edn2-KO_homozygous
Edn2-KO_WT
Emx1-Cre_heterozygous
Emx1-Cre_homozygous
Emx1-Cre_WT
Epha1 -P460L_heterozygous
Epha1 -P460L_homozygous
Epha1 -P460L_WT
Epha1-KI_heterozygous
Epha1-KI_homozygous
Epha1-KI_WT
Epha1-KO_heterozygous
Epha1-KO_homozygous
Epha1-KO_WT
Erc2-KI_heterozygous
Erc2-KI_homozygous
Erc2-KI_WT
Erc2-KO_heterozygous
Erc2-KO_homozygous
Erc2-KO_WT
Gad2-Cre_heterozygous
Gad2-Cre_homozygous
Gad2-Cre_WT
Gamma_heterozygous
Gamma_homozygous
Gamma_WT
Gpnmb_heterozygous
Gpnmb_homozygous
Gpnmb_WT
Gpnmb-pyro_heterozygous
Gpnmb-pyro_homozygous
Gpnmb-pyro_WT
Gpnmb-SEQ_heterozygous
Gpnmb-SEQ_homozygous
Gpnmb-SEQ_WT
hAbeta-KI_LoxP_heterozygous
hAbeta-KI_LoxP_homozygous
hAbeta-KI_LoxP_WT
hAPP-3/3_heterozygous
hAPP-3/3_homozygous
hAPP-3/3_WT
hAPP-Arc_heterozygous
hAPP-Arc_homozygous
hAPP-Arc_WT
hAPP-Aus_heterozygous
hAPP-Aus_homozygous
hAPP-Aus_WT
hAPP-KO_heterozygous
hAPP-KO_homozygous
hAPP-KO_WT
hAPP-SFL_heterozygous
hAPP-SFL_homozygous
hAPP-SFL_WT
hAPP-Swe_heterozygous
hAPP-Swe_homozygous
hAPP-Swe_WT
hTau-H1_heterozygous
hTau-H1_homozygous
hTau-H1_WT
hTau-H2_heterozygous
hTau-H2_homozygous
hTau-H2_WT
I134-KO_heterozygous
I134-KO_homozygous
I134-KO_WT
IL1rapb-cKO_heterozygous
IL1rapb-cKO_homozygous
IL1rapb-cKO_WT
IL1RAPex2-KO_heterozygous
IL1RAPex2-KO_homozygous
IL1RAPex2-KO_WT
IL1RAPex3-KO_heterozygous
IL1RAPex3-KO_homozygous
IL1RAPex3-KO_WT
J20_carrier
J20_noncarrier
Kif21b-KI_heterozygous
Kif21b-KI_homozygous
Kif21b-KI_WT
Kif21b-KO_heterozygous
Kif21b-KO_homozygous
Kif21b-KO_WT
Lyz2_heterozygous
Lyz2_homozygous
Lyz2_WT
mApoe_heterozygous
mApoe_homozygous
mApoe_WT
mApoe-KO_heterozygous
mApoe-KO_homozygous
mApoe-KO_WT
Meox2-Cre_heterozygous
Meox2-Cre_homozygous
Meox2-Cre_WT
mTau_heterozygous
mTau_homozygous
mTau_WT
mTau-KO_heterozygous
mTau-KO_homozygous
mTau-KO_WT
Mthfr-KI_heterozygous
Mthfr-KI_homozygous
Mthfr-KI_WT
Mthfr-KO_heterozygous
Mthfr-KO_homozygous
Mthfr-KO_WT
Mtmr4-KI_heterozygous
Mtmr4-KI_homozygous
Mtmr4-KI_WT
Mtmr4-KO_heterozygous
Mtmr4-KO_homozygous
Mtmr4-KO_WT
mTrem2-KO_heterozygous
mTrem2-KO_homozygous
mTrem2-KO_WT
Nes_heterozygous
Nes_homozygous
Nes_WT
NPC_heterozygous
NPC_homozygous
NPC_WT
Picalm-H458R_heterozygous
Picalm-H458R_homozygous
Picalm-H458R_WT
Plcg2-KI_heterozygous
Plcg2-KI_homozygous
Plcg2-KI_WT
Plcg2-KO_heterozygous
Plcg2-KO_homozygous
Plcg2-KO_WT
Plp1_heterozygous
Plp1_homozygous
Plp1_WT
Psen1-3xTG_carrier
Psen1-3xTG_noncarrier
PSEN1-KI_heterozygous
PSEN1-KI_homozygous
PSEN1-KI_WT
PSEN1dE9_carrier
PSEN1dE9_noncarrier
Ptprb-KI_heterozygous
Ptprb-KI_homozygous
Ptprb-KI_WT
Shc2-KI_heterozygous
Shc2-KI_homozygous
Shc2-KI_WT
Shc2-KO_heterozygous
Shc2-KO_homozygous
Shc2-KO_WT
Snx1-KI_heterozygous
Snx1-KI_homozygous
Snx1-KI_WT
Sorl1-KI_heterozygous
Sorl1-KI_homozygous
Sorl1-KI_WT
Sorl1-KO_heterozygous
Sorl1-KO_homozygous
Sorl1-KO_WT
Sox2-Cre_heterozygous
Sox2-Cre_homozygous
Sox2-Cre_WT
Spi1-rs1377416_heterozygous
Spi1-rs1377416_homozygous
Spi1-rs1377416_WT
Stat3-FLX_heterozygous
Stat3-FLX_homozygous
Stat3-FLX_WT
Stat3-KO_heterozygous
Stat3-KO_homozygous
Stat3-KO_WT
Thy1_heterozygous
Thy1_homozygous
Thy1_WT
Tie2-GFP_heterozygous
Tie2-GFP_homozygous
Tie2-GFP_WT
TM1A_carrier
TM1A_noncarrier
TM1C_carrier
TM1C_noncarrier
TM1D_carrier
TM1D_noncarrier
TMEM119_heterozygous
TMEM119_homozygous
TMEM119_WT
Trem2-R47H_heterozygous
Trem2-R47H_homozygous
Trem2-R47H_NSS_heterozygous
Trem2-R47H_NSS_homozygous
Trem2-R47H_NSS_WT
Trem2-R47H_WT
XFP_heterozygous
XFP_homozygous
XFP_WT

genotypeBackground

Genetic background of the model

C57BL6J (#000664) C57BL6N (#005304)
Expand
titleMODEL-AD-approved Values with JAX stockNumber(s)

C57BL6J
C57BL6N
CC037
CC041
CC013
CC006
CC002
CC017
B6JCC037
B6JCC041
B6JCC013
B6JCC006
B6JCC002
B6JCC017
LOAD1
LOAD2

Expand
titleValues with JAX stockNumbers of background strains

C57BL6J C57BL6N C57BL6J:C57BL6N CC037 CC041 CC013 CC006 CC002 CC017 B6JCC037 B6JCC041 B6JCC013 B6JCC006 B6JCC002 B6JCC017 LOAD1 LOAD2

C57BL6J (000664) C57BL6N (005304)
C57BL6J:C57BL6N (#000664 & #005304) CC037 (#025423) CC041 (#021893) CC013 (#021892) CC006 (#022869) CC002 (#021236) CC017 (#022870) B6JCC037(#000664 & #025423) B6JCC041(#000664 & #021893) B6JCC013(#000664 & #021892) B6JCC006(#000664 & #022869) B6JCC002(#000664 & #021236) B6JCC017(#000664 & #02870)
LOAD1 (#028709028709)
LOAD2-- (#030670)

Expand
titleControlled Values

030670)

individualCommonGenotype

Genotype of animal with LOAD-terminology

LOAD1:

  • APOE4_homozygous

  • TREM2R47H_homozygous

LOAD2:

  • APOE4_homozygous

  • TREM2R47H_homozygous

  • ABETA_homozygous

Controlled values
Expand
titleControlled Values

LOAD1
LOAD2
LOAD1.ABCA7A1527G
LOAD1.CEACAM1KO
LOAD1.Clasp2L163P
LOAD1.CR1long
LOAD1.Il1rapExon2KO
LOAD1.MthfrC677T
LOAD1.Plcg2M28L
LOAD1.Snx1D465N
Trem2R47H
C57BL6J
5XFAD
APOE4

officialName

Official JAX Mice strain nomenclature.

Full name indicating all transgenes.

https://mice.jax.org

  • C57BL/6J

  • B6(SJL)-Apoetm1.1(APOE*4)Adiuj Trem2em1Adiuj/J

modelSystemName

Strain annotation

Values: https://www.synapse.org/#!Synapse:syn10242922/tables/query/eyJzcWwiOiJTRUxFQ1QgRElTVElOQ1QgIHZhbHVlIEZST00gc3luMTAyNDI5MjIgV0hFUkUgKCggXCJrZXlcIiA9ICdtb2RlbFN5c3RlbU5hbWUnICkgKSIsICJhZGRpdGlvbmFsRmlsdGVycyI6W10sICJpbmNsdWRlRW50aXR5RXRhZyI6dHJ1ZSwgIm9mZnNldCI6MCwgImxpbWl0IjoyNSwgInNvcnQiOltdfQ==

Example: 3xTg-AD

stockNumber

The JAX stock number (6-digit)

Example: 030283 000664