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Not directly. Synapse helps you manage User Content, including Data, analysis, tools, methods,  and  and results. However, using the programmatic interfaces built into Synapse makes it easy to set up analytical pipelines and ad hoc analyses that interact with Synapse. By default, Synapse uses Amazon’s cloud infrastructure (S3) for storage, making it simple to allocate large compute resources and collocate them next to User Content storage.

Synapse does support users performing analysis on data stored in S3 buckets in Synapse using the AWS Security Token Service (STS). (see Computing Directly on Data in Synapse In S3)

The Terms and Conditions of Use fully Use fully describes the governance terms and conditions of Synapse. In order to register on Synapse, you must review and agree to the terms of the Synapse Awareness and Ethics Pledge. For more information, see Synapse Governance.

Synapse was developed with the philosophy to encourage collaboration across institutional boundaries and is therefore provided as “Software As A Service” with a single instance used by all users. This makes it easy both to discover new content and share with new collaborators. We do support private project spaces where content sharing is controlled by the individual user. In addition, Synapse has the ability to reference resources that are stored elsewhere. This allows Synapse to store metadata about the content such as annotations, descriptive wiki pages and provenance but not the actual data. Currently Synapse has specific support for files stored at URLs, on SFTP servers, on AWS S3 and arbitrary file servers (see: /wiki/spaces/DOCS/pages/2048327803Custom Storage Locations).

Validating your profile is a process where your identity is established through a combination of your profile information, ORCID, and an external credential. Validation increases transparency between researchers and User Content donors. A validated profile is needed for access to specific User Content and is currently required for access to User Content collected through Sage Bionetworks’ research apps. Profile validation instructions can be found in the Settings tab of your Synapse profile page. Click the “Request Profile Validation” link for the required steps.

This will depend if depends on whether the content is public or private. If private, you will need to make sure your colleague has shared this content with you. Shared content is visible from your “Dashboard page” under the tab “Shared directly with me”. If you favorite the content (using the star) it will appear under your list of favorites visible from the /wiki/spaces/DOCS/pages/2048557182 or on your /wiki/spaces/DOCS/pages/2055405596.

All public data is queryable. For more information see /wiki/spaces/DOCS/pages/2667642897 or from the “Search” box in the top right corner of any Synapse page.

Sage offers the following service plans: (1) a Basic Hosting Plan, (2) a paid-for Self-Managed Plan, and (3) a paid-for, customized, Data Coordination Plan.  The Sage Terms of Service apply to each of these plans unless otherwise noted.  Additional governance terms may apply.

Basic Hosting Plan

1. Included Services

The Basic Hosting Planis intended for users wanting to share small datasets for scientific, educational, research collaborations, and publications (including creating DOIs) purposes.  This plan includes:

• User Content hosting of up to 100GB of space

• Egress capped at 4TB/year

• Self-service Project set-up with no direct support from Sage staff

• A basic portal landing page (Wiki)

• Users can create Projects with administrative control over who is granted access to each Project

2. User Content Longevity

Sage will continue to host User Content in a Basic Hosting Plan for as long as the User Content is being viewed or accessed.  Sage currently utilizes Amazon Web Services (AWS) Intelligent-Tiering storage in all service plans.  Infrequently accessed User Content will be moved to access tiers that require longer retrieval times. 

Sage may, at its own discretion and with notice to the Project Administrator, implement cost mitigation strategies, including, for example, moving User Content to lower-cost hosting services or employing fee sharing if such User Content accumulates high egress charges.

Sage reserves the right to delete User Content, including Private Content, if deemed inappropriate or if it conflicts with the Sage Terms of Service or at Sage’s discretion, after 24 months of inactivity (i.e., User Content is not viewed or downloaded).  Sage will reach out to the Project Administrator of the User Content at least two times (at the email address provided upon registration) warning that the User Content may be removed if the user does not respond with a proposed use case for the User Content.  If the Project Administrator does not respond within 30 days of the second warning, Sage has the right to delete the User Content.

3. Third-party access to User Content Hosted in a Basic Hosting Plan

Project Administrators are expected to respond to inquiries from Sage or other Synapse users without delay.  If Sage receives complaints that a Project Administrator is not responding to inquiries, Sage will assume the Project Administrator’s account is inactive and reserves the right to suspend the Project Administrator’s account.

Self-Managed Plan

1. Included Services

The Self-Managed Plan includes: 

• Option 1: User Content hosting of up to 100GB of space; Egress capped at 4TB /year .

• Option 2: User Content hosting of up to 500GB of space; Egress capped at 20TB/ year.

• Up to 15 hours of consulting services, including for setting up Projects and sharing User Content according to the F.A.I.R. principles and governance

• Up to 25 hours of help desk support

• Tools for self-managing User Content access requests

• A basic portal landing page (Wiki)

• Users can create Projects where they have administrative control over who is granted access to each Project and can deploy User Content restrictions by clickwrap agreements.

2. User Content Longevity

Sage will keep User Content in a Self-Managed Plan for 5 years (or as otherwise negotiated).  Sage utilizes Amazon Web Services (AWS) Intelligent-Tiering storage in all of the service plans.  Infrequently accessed User Content will be moved to access tiers that require longer retrieval times.  

After the Self-Managed Plan expires, the Self-Managed Plan account holder will have 3 months to retrieve or make other arrangements with regard to their User Content or to renew the Self-Managed Plan.  After this 3-month grace period, if the account holder does not retrieve or make other arrangements with regard to their User Content or renew the Self-Managed Plan, Sage reserves the right, at its sole discretion, to archive, freeze, delete, or move the User Content.  For example, if the User Content meets the criteria, Sage may move the User Content to a Basic Hosting Plan or to the AWS Open Data (or a similar) program.

3. Third-Party Access to User Content Hosted in a Self-Managed Plan

Project Administrators are expected to respond to inquiries from Sage or other Synapse Users without delay.  If Sage receives complaints that a Project Administrator is not responding to inquiries, Sage will try to reach out to such Project Administrator, and to the institution associated with the Self-Managed Plan account.  If the Project Administrator and institution are not responsive, Sage reserves the right to suspend the Self-Managed Plan account. Sage will not provide a refund if a Self-Managed Plan is suspended for failure to meet service level expectations.

If you have a Self-Managed or Data Coordination Custom Plan, Sage can help you prepare materials for your data management and sharing plan and budget. We provide quotes for services for use in your budget and standardized text for your plan. To start, Contact Us.

These are the general storage limitations for each plan: up to 100GB for Basic Hosting Plan and up to 500GB for the Self-Managed Plans. You may pay for additional storage if needed. Please see our Sage Offerings page for more information. There are no data limits if you use Custom Storagein your own cloud bucket, and depending on the dataset uploaded, storage may be sponsored by an existing project.   Contact us to learn more.