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titleWhat does Synapse do?

Synapse allows researchers to share and describe data, analyses, and other content. Data and analyses can be stored in many types of locations, including private servers, local hard drives, or cloud storage. Synapse provides a common interface to describe these data or analyses, where they come from, and how to use them. Synapse also provides mechanisms for adding and retrieving data, analyses, and their respective descriptions. For a comprehensive introduction to Synapse see our Getting Started guide.

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titleHow much does it cost to use Synapse?

We allow groups to get started for free by subsidizing relatively moderate amounts of internal Synapse cloud storage (e.g. 10s of GB). If your needs will exceed this limit we suggest contacting SynapseInfo@sagebase.org for other solutions, including the ability for groups to host their own content either in cloud storage, proxied from /wiki/spaces/DOCS/pages/2048327803 or as external links.

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titleWhat are the Synapse Terms of Use?

The Terms and Conditions of Use fully describes the governance terms and conditions of Synapse. In order to register on Synapse, you must review and agree to the terms of the Synapse Awareness and Ethics Pledge. For more information see the complete Synapse Governance policies, see /wiki/spaces/DOCS/pages/2004255211.

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titleIs Synapse open source?

Yes, Synapse is released under the Apache 2.0 License The source code is available on GitHub. Synapse is also offered free of charge as a hosted Software as a Service (SaaS) at https://www.synapse.org/.

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titleHow do I get started?

See /wiki/spaces/DOCS/pages/2055471150 for a breakdown of what you need to get started and how to make the most of Synapse.

Whether you are looking to access content or use Synapse to track your own work, start by registering for a Synapse user account. Before uploading files, you will need to take a short certification quiz that demonstrates your understanding of the ethical considerations in sharing data and the manner in which data is managed and shared in Synapse. See the Getting Started guide for tips on how to access data, create your own project, and share content with others.

Accessing Content

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titleMy colleague put some content in Synapse. How do I find it?

This will depend if the content is public or private. If private, you will need to make sure your colleague has shared this content with you. Shared content is visible from your “Dashboard page” under the tab “Shared directly with me”. If you favorite the content (using the yellow star) it will appear under your list of favorites visible from the top of any Synapse page /wiki/spaces/DOCS/pages/2048557182 or on your Profile/wiki/spaces/DOCS/pages/2055405596.

All public data is queryable. For more information see help on querying/wiki/spaces/DOCS/pages/2667642897 or from the “Search” box in the top right corner of any Synapse page.

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titleWhat is a validated profile?

Validating your profile is a process where your identity is established through a combination of your profile information, your ORCID, a signed Synapse Pledge, and an external credential. Validation increases transparency between researchers and data donors. A validated profile is needed for access to specific datasets, and is currently required for access to data collected through Sage Bionetworks’ research apps. Profile validation instructions can be found in the Settings tab of your Synapse your Synapse profile page. Click on the ‘Request Profile Validation’ link to see the required steps.

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titleI'm ready to share data, how do I start?

Synapse makes it easy to share files of any sort, with whomever you choose whether a small group of collaborators or the general public. You may share raw data, summarized data, analysis results, or anything in between. We recommend using Quick Start Guide for more details on how to upload and manage contentSee /wiki/spaces/DOCS/pages/2002846338 for information and instructions on sharing your data.

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titleWhy do I have to be a certified user to upload content?

User certification ensures that you understand your responsibilities for sharing data through Synapse, especially data derived from human participants. These responsibilities include making sure that data derived from human participants is de-identified and that all applicable privacy laws and regulations are observed. See the How to contribute data for more information.

To become a certified user, you will need to pass a brief quiz.

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titleIs everything I share on Synapse public?

No. Use sharing settings to control who can see the content you create. By default, projects and their content are visible only to the user who created it. By using the Synapse sharing settings, you have the ability to grant other Synapse users, Synapse teams, or the public access to your Project content. You can learn more here: /wiki/spaces/DOCS/pages/20149046112024276030.

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titleCan I store sensitive information about human subjects in Synapse?

Yes. Synapse has an IRB-approved data governance procedure that employs Conditions for Use to allow for the sharing of sensitive data in a controlled manner. You can learn more by reading our  /wiki/spaces/DOCS/pages/2024276030 and /wiki/spaces/DOCS/pages/2014904611 documentation and Governance documentation2004255211. If you have questions or would like assistance in applying Conditions of Use to your data, please contact the Synapse Access and Compliance Team at act@sagebase.org.

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