Page Comparison

Variable

Definition

Example

genotype

Genotype of animal that indicates littermate carriers vs noncarriers.

Format based on Climb variables: <gene>-<allele>_<genotype_symbol>

Complete list of genotype values

• APOE4-KI_heterozygous

• APOE4-KI_homozygous

• APOE4-KI_WT

• 3xTg-AD_carrier

• 3xTg-AD_noncarrier

officialName

Full name indicating all transgenes, taken from the strain’s JAX datasheet

• B6.Cg-Apoetm1.1(APOE*4)Adiuj

• Abca7em2Adiuj Trem2em1Adiuj/J

modelSystemName

Strain annotation - see AMP-AD Metadata Dictionary. Used as file annotation

Abca7A1527GAPOE4Trem2R47H

See data query

stockNumber

The JAX stock number

030283

genotypeBackgroundBackground genotype

Genetic background of the model

C57BL6J

individualCommonGenotype

Genotype of animal with LOAD

terminology (used by MODEL-AD Explorer)

LOAD1:

• APOE4_homozygous

• TREM2R47H_homozygous

LOAD2:

• APOE4_homozygous

• TREM2R47H_homozygous

• ABETA_homozygous
  

• 5XFAD

• APOE4

• C57BL6J

• LOAD1

• LOAD1.ABCA7A1527G

• LOAD1.CEACAM1KO

• LOAD1.CR1long

• LOAD1.Clasp2L163P

• LOAD1.Il1rapExon2KO

• LOAD1.MthfrC677T

• LOAD1.Plcg2M28L

• LOAD1.Snx1D465N

• LOAD2

• Trem2R47H