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Uploading Animal Model Documentation
Mouse Model Description
This article will teach you how to submit share new rodent animal models to with the AD Knowledge Portal’s Data Coordination Center (AD-DCC) at Sage Bionetworks. To start,
MODEL-AD teams must should inform the AD-DCC about new models by submitting a complete and accurate description via the MODEL-AD Tools survey. The content entered into the survey will be used to populate the corresponding Experimental Tool card Tools listed in the AD Knowledge Portal.
Animal Model Content
Each mouse model should be accompanied by include a brief study description that includes the species, genetic background, a link to the Jax Datasheet (if available) or a description of how the animals were created .
Metadata Key Variables
Mouse models must include the information and the key details listed below. The model information details should match that the information on the Jackson labs stock pages, and any discrepancies will need to be resolved. If you have any questions, please contact the DCC before submitting.
Email address for contact person
Grant number
Species
Model Common Name
Model URL (link to the stock number in the Jackson Lab databasemodel, eg, https://www.jax.org/strain/031988 )
Report card URL (link to the AlzForum model: https://www.alzforum.org/research-models/ )
Model description (<500 characters)
Targeted Genes
Background strain
Type (LOAD – Late Onset ADAlzheimer’s Disease, FAD – Familial ADAlzheimer’s Disease)
Create Model Entity in Experimental Tools
The Sage AD-DCC will create a new entity in the AD Knowledge Portal’s Synapse Experimental Tools file view. The new entity will be named after the Model Common Name and will include a link to the corresponding Jackson labs Model URL webpage.
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