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This article will teach you how to share your MODEL-AD animal models (ie, experimental tools) with the AD Knowledge Portal’s Data Coordination Center (AD-DCC) at Sage Bionetworks.

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MODEL-AD teams should inform the AD-DCC about new models by submitting a complete and accurate description via completing the MODEL-AD Tools survey. The descriptive content entered into the survey will be used to populate the corresponding Experimental ToolsTool cards listed in the AD Knowledge Portal.

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Model Information to include

• Email address for contact personthe team’s data liaison

• Grant number

• Species

• Model Common Name

• Model URL (link to the Jackson Lab model, eg, https://www.jax.org/strain/123456 )

• Report card URL (link to the AlzForum model: https://www.alzforum.org/research-models/ )

• Model description (<500 characters)

• Targeted Genes

• Background strain

• Type (LOAD – Late Onset Alzheimer’s Disease, FAD – Familial Alzheimer’s Disease)

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1. Navigate to the Experimental Tools file view

2. Download the Experimental Tool

   1. Click Download Options > Export Table

   2. Click Download as CSV

3. Add annotations to CSV file using a text editor or spreadsheet software

4. Upload your revised CSV to the entity view to populate annotations

Link to Experimental Study

Sage The AD-DCC enters link to study with the data available for the model.

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will link all of the data in Synapse that uses the model. This is a Synapse file view that includes a query for all data associated with the model and will not be limited to individual studies.

1. Navigate to …

Create and share Model release notes

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