Describe Mouse Model in MODEL-AD Tools Survey
This article will teach you how to submit new mouse rodent models to the Data Coordination Center (DCC) at Sage Bionetworks.
Submit new mouse model
The first step is for the MODEL-AD teams to provide information for the AD Knowledge Portal Cards by describing available MODEL-AD generated mouse models. MODEL-AD teams need to submit this mouse model description in must inform the DCC about new models by submitting a complete and accurate description via the [MODEL-AD Tools survey](https://docs.google.com/forms/d/e/1FAIpQLSfP0jZf_XZKP5Kqvf8GZbZgntCMAnAgDQww9e0jhsweqOYGqw/viewform) survey when new models are available.. The content entered into the survey will be used to populate unique model card in the AD Knowledge Portal.
Metadata Key Variables
Mouse models must include the following information: mouse model names, strain names, stock numbers, and target genes. This . The information should match the information that on the Jax Jackson labs stock pages. Target genes also Any discrepancies will need to be included.resolved.
Email address for contact person
Grant number
Species
Model Common Name
Model URL (link to the Jax strain database)
Report card URL (link to the AlzForum)
Model description (<500 characters)
Targeted Genes
Background strain
Type (Late Onset AD, Familial AD)
Create Experimental Study in Experimental Tools
The Sage DCC creates a dummy folder in the [Experimental Tools file view](https://www.synapse.org/#!Synapse:syn22219740)
Annotate the Experimental Study
Link to Experimental Study
Sage DCC enters link to study with data available on the model.
Sage DCC writes release notes to inform the community a new model is available.
MODEL-AD teams provide mouse model reports
Mouse model information should be provided in a PDF. Sage DCC will link to this PDF to the mouse model card in Synapse.
Create Jira ticket and assigned to Director. Once approved this will be assigned to the governance team to set permissions accurately for files. Some files will be publicly viewable and will need approval by the governance team to be allowed. This occurs at the file, not folder level.
Sage team links mouse model report
Sage DCC uploads reports to [MouseModelReports](https://www.synapse.org/#!Synapse:syn25474060 )
Sage DCC requests necessary permissions
Sage DCC requests that the PDF model report is permitted to be publicly available in Sage without restriction. [Enable Anonymous Download of Synapse Data](How to Enable Anonymous Download of Synapse Data )
Sage DCC updates file view with link to model report
Sage DCC updates file view with a link to the mouse model report in the [Portal - Experimental Tools](https://www.synapse.org/#!Synapse: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 )
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