How: extract first principal components of each module and correlate it with known clinical traits (survival, cancer stage, cancer grade, age). All analyses were done in the same way as it was done here. Here is a table with P values:

Survival: none

Age: brown, grey

Primary therapy outcome: none

Tumor Grade: brown

Tumor residual disease: none

Tumor Stage: none

Brown module is enriched in the following GO categories: membrane-bounded organelle, intracellular membrane-bounded organelle, glutamate dehydrogenase activity, glutamate dehydrogenase [NAD(P)+], activity, oxidoreductase activity, leucine binding, central nervous system neuron development, guanylate kinase activity, organelle, nucleolus. Smallest GO enrichment P value after multiple testing correction is 1.19E-02.

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