Rubrics (WIP)

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Antibodies:

• must pass schematic validation

• epitope should be formatted using the following style:

  • if phospho-specific, have the prefix “phospho-” followed by

  • gene symbol/protein symbol e.g. “NF2” followed by

  • if phospho-specific, should label the phospho-target in parentheses with the three-character amino acid (aa) abbreviation followed by the location e.g. “(Ser2515)” followed by

  • if mutation-specific, should label the protein variant using one-character aa abbreviation eg. “(G12V)” followed by

  • if available, aa location of target in parentheses in the format of (aa START-END) e.g. “(aa 100-150)” or “(aa 507-530 N-term)”

  • examples of valid epitopes:

    • NF1

    • phospho-NF1 (Ser2515)

    • KRAS (G12V)

    • NF1 (aa 100-150)

    • NF1 (aa 507-530 N-term)