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Laird (2006, 2011) markers
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Laird (2006, 2011) markers

Owned by Vitalina Komashko (Unlicensed)
Last updated: Apr 10, 2012Version comment

In contrast to Shen, 2007 paper Weisenberger, 2006 identified a smaller set of markers: CACNA1G, IGF2, NEUROG1, RUNX3, SOCS1 and MLH1 as CIMP in colorectal patients. These markers were also confirmed in Hinoue, 2011 paper. In 2006 paper they weren't able to confirm Shen's markers.

CpGs mapped to the 5 genes on 27 k platform:

probe_id gene_id  symbol
5524  cg05942574    8913 CACNA1G
10454 cg11262815    8913 CACNA1G
17291 cg18454685    8913 CACNA1G
4594  cg04897683    4762 NEUROG1
10437 cg11248413    4762 NEUROG1
16710 cg17830308    4762 NEUROG1
5592  cg06037693     864   RUNX3
12515 cg13461622     864   RUNX3
13229 cg14182690     864   RUNX3
15532 cg16529592     864   RUNX3
457   cg00487159    8651   SOCS1
5834  cg06295404    8651   SOCS1
24322 cg26012103    8651   SOCS1
24608 cg26301908    8651   SOCS1
3722  cg03956628    4292    MLH1
10187 cg10990993    4292    MLH1
22991 cg24607398    4292    MLH1