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Participants will be provided with a whole cell model of Mycoplasma genitalium and tasked with estimating the model parameters for specific biological processes from simulated data. The simulated data to be provided represents possible measurements in actual experiments: participants will will have a credit budget and will be able to purchase simulated data on demand with the aim to refine the parameters under estimation.
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About DREAM Challenges
Sage Bionetworks and DREAM are convinced that running open computational Challenges focused on important unsolved questions in systems biomedicine can help advance basic and translational science. By presenting the research community with well-formulated questions that usually involve complex data, we effectively enable the sharing and improvement of predictive models, accelerating many-fold the analysis of such data. The ultimate goal, beyond the competitive aspect of these Challenges, is to foster collaborations of like-minded researchers that together will find the solution for vexing problems that matter most to citizens and patients.
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Synapse is an open computational platform designed to facilitate new ways for data scientists to work with data and with each other. Synapse reinforces the power of DREAM Challenges to catalyze a diverse community of researchers to nucleate around a particular scientific question. Synapse’s engaging features such as real-time leaderboards, code-sharing, and provenance tracking incentivize continuous participation in DREAM Challenges. Participants can accelerate scientific progress by generating, sharing, and evolving thousands of predictive models in real time that would have otherwise taken years to produce.
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