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MODEL-AD study names should be formatted as follows.

Study type

Naming Format

Number of Strains

Primary Screen

Site_PrimaryScreen

  • Jax.IU.Pitt_PrimaryScreen

  • UCI_PrimaryScreen

Many

Strain Validation

Site_StrainValidation

  • Jax.IU.Pitt_StrainValidation

  • UCI_StrainValidation

Many

Deep Phenotyping

Site_Model

  • Jax.IU.Pitt_APOE4_Trem2

  • UCI_5XFAD

Many

Pharmacokinetic

Site_Model_Drug

  • Jax.IU.Pitt_5XFAD_Verubecestat

One

Pilot Studies

  • Microbiome

  • Proteomics

  • Metabolomics

Site_StudyType_Pilot

Examples:

  • Jax.IU.Pitt.Proteomics_Metabolomics_Pilot

Many

Contributing Data Files to Synapse

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Study directories will be organized like this:

  • Study_Name/

    • Data/

      Assay_a/

    • Assay_b/

    • Metadata/

    • Staging/ (pre-releaseprivate access)

File naming

File names must be unique and machine readable. Names can not include special characters. Furthermore, we recommend the names be concise and descriptive.

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MODEL-AD specific templates are being drafted and will be made available on Synapse (see Study, Acknowledgment, and Methods). Each study should be accompanied by needs a brief study description that includes the species, genetic background, a link to the Jax Datasheet (if available) or a description of how the animals were created.

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Methods Description

Each assay should include a brief description of the procedures, data collection, and analytical methods. This is a good opportunity to provide useful details that may not be included in the manuscript.

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