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We use a customized Bootstrap theme in the SWC, which we then further customize to have the a different color palette.  Do this when updating Bootstrap.

Step

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by

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step guide

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-@brand-primary:         #2196F3;
-@brand-success:         #4CAF50;
-@brand-info:            #9C27B0;
-@brand-warning:         #ff9800;
-@brand-danger:          #e51c23;

+@brand-primary:         #207da8;
+@brand-success:         #17a666;
+@brand-info:            #7772b4;
+@brand-warning:         #f19223;
+@brand-danger:          #d9534f;

Also, update the tooltip background color

-@tooltip-bg:                  #727272;
+@tooltip-bg:                  #171717;

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is provided in the repo page (under Synapse customization).

https://github.com/Sage-Bionetworks/bootswatch