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Welcome to the MODEL-AD Documentation site!

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This platform provides instructions on how to contribute data and metadata concerning your MODEL-AD research studies (eg, mouse models, protocols, metadata, and data)activities. The main goal of MODEL-AD is to standardize simplify the process of characterizing animal models, establish guidelines standards for preclinical testing, and ensure the availability of that animal models, protocols, and validated data are easily accessible to all researchers for engaged in drug development.

Explore MODEL-AD Research Assets

How to contribute data and metadata

To contribute data and metadata, create a Synapse account and join the MODEL-AD team.

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• MODEL-AD Program on the AD Knowledge Portal

• Projects

  • The JAX.IU.Pitt Alzheimer's Disease Precision Models Center

  • UC Irvine AD Translational Center For Disease Model Resources

• MODEL-AD Studies

• Experimental Mouse Models

• Data (including gene expression, immunoassay, proteomic, behavioral, and more)

• MODEL-AD Explorer

Learn more about

• Contributing Data

• The MODEL-AD Team

Synapse Account

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Team members that will be involved in data contribution and attributed on the portal need to register for a Synapse account. Profiles should include your full name, institution, photo, and a brief bio.

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Uploaders must become Certified Users and request membership to the MODEL-AD Data Upload Team.

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Learn about the Team and Responsibilities

Synapse accounts will be

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Added to the Explore People page

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Linked with the grant in the portal (eg, U54AG054345)

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Follow these steps to register for a synapse.org account, join the MODEL-AD Team, contribute data, prepare metadata, and upload data.

1. Register for a synapse.org account

   1. Visit the Synapse website and locate the "Register Now" button.

   2. Fill in your desired username and email address.

   3. Expect to receive an email from Synapse containing further instructions on finalizing your registration.

2. Join the MODEL-AD Team

   1. After successfully registering for a Synapse account, navigate to the "Teams" tab and search for "MODEL-AD_DataUpload" to join the team.

   2. Simply click on the "Join Team" button.

   3. Optionally, include a message and then proceed by clicking on the "Send request" button.

3. Contributing data to the portal

   1. As a member of the MODEL-AD Team, you can contribute data to the portal by selecting the "Contribute Data" option.

   2. Provide necessary details about your data, such as data type, size, and format.

   3. Additionally, furnish a citation for your data.

   4. Finally, submit your data by clicking on the "Submit Data" button.

What data and metadata can I contribute?

You can contribute any data and metadata that is relevant to your MODEL-AD research studies. This includes data on mouse models, protocols, and validated data.

What are the benefits of contributing data and metadata?

By contributing data and metadata, you can help to advance the field of Alzheimer's disease research. Your data and metadata will be made available to other researchers, which will help them to develop new treatments for Alzheimer's disease.

How do I contribute data and metadata?

• Contributing data to the portal

• Preparing Metadata

• Preparing and uploading Data

How can I learn more?

If you have any questions about contributing data and metadata, please contact the MODEL-AD team.

• Who is involved in MODEL-AD?

  • The JAX.IU.Pitt Alzheimer's Disease Precision Models Center

  • UC Irvine AD Translational Center For Disease Model Resources

• MODEL-AD data is available here: AD Knowledge Portal – MODEL-AD

  • Studies

  • Search for Data

  • Explore the Experimental Models used to target AD-genes

• Explore the the AD-related biomarker data in our https://modeladexplorer.org/

Thank you for your contribution!