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Dataset

# Probes

# Samples

 

Sage Time

Sage Space

Package Time

Package Space

Sage Beta

Package Beta

Gene trees same?

Module difference (%)

Female mouse liver

3600

135

 

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Methylation (gene subset)

??

555

 

 

 

 

 

 

 

 

 

Colon cancer (small gene subset)

??

322

 

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Cranio

2534

249

 

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Methylation (full set)

27,578

5555

 

 

 

 

 

 

 

 

 

Colon cancer (large gene subset)

 

322

 

 

 

 

 

 

 

 

 

Human liver cohort

40,102

427

 

 

 

 

 

compute correlation coefficient

determine optimal value for beta

compute TOM

perform hierarchical clustering over TOM  (using 'hclust')

detect and label modules in TOM (using 'cutreeDynamic')  

 

 

 

Note: We skip the performance evaluation for the small data sets.