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We are trying to evaluate which method is the most appropriate for normalization. Here we are going to compare each method "performance" by identifying the number of loci associated with age and finding an overlap and associated P-values with each overlap.

Overlap:

http://genome.cshlp.org/content/early//03/09/gr.103606.109] 

  age

Level 2

Level 1 Level1 -lumi

snm (meth.probes only)

[ Teschendorff, 2010

2010

||
| Level 2 | | | | |
| Level 1

101

Level1 - lumi | | | | |

89

| snm (meth.probes only) | | | | |
| [

Teschendorff, 2010

http://genome.cshlp.org/content/early/2010/03/09/gr.103606.109]

 

 

 

P-values (significance overlap)