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If you want to sign up for one of these Challenges, please click on the respective Challenge link.
HPN-DREAM Breast Cancer Network Inference Challenge
Participants in this Challenge will be provided with an extensive proteomics time-course dataset on four breast cancer cell lines and tasked with analyzing these data to solve the following 3 sub-challenges: 1) build network models that represent the active cell signaling pathways in breast cancer, 2) predict the dynamic response of various phospho-proteins to drug perturbations, and 3) propose novel strategies to visualize these high dimensional data.
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Participants will be provided with a whole cell model of Mycoplasma genitalium and tasked with estimating the model parameters from simulated data for specific biological processes. The simulated data to be provided represents possible measurements in actual experiments: participants will be able to purchase this on demand with the aim to refine the parameters under estimation.
About DREAM Challenges
Sage Bionetworks and DREAM are convinced that running open computational Challenges focused on important unsolved questions in systems biomedicine can help advance basic and translational science. By presenting the research community with well-formulated questions that usually involve complex data, we effectively enable the sharing and improvement of predictive models, accelerating many-fold the analysis of such data. The ultimate goal, beyond the competitive aspect of these Challenges, is to foster collaborations of like-minded researchers that together will find the solution for vexing problems that matter most to citizens and patients.
DREAM-DEMO-J
DREAM8 Press Releases
Click here to read the Heritage Provider Network press release
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