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Welcome to the MODEL-AD Documentation site!

This site exists to help orient you to the procedures related to contributing information provides information on how to contribute data and metadata about your MODEL-AD research studies (eg, mouse models, metadata, and data). The goal of MODEL-AD is to standardize the process of characterizing animal models, establish guidelines for preclinical testing, and ensure the availability of animal models, protocols, and validated data to all researchers for drug development.

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How to contribute data and metadata

To contribute data and metadata, you will need to create a Synapse account and join the MODEL-AD team. Here are the steps on how to register for a synapse.org account, join the MODEL-AD Team, contribute data to the portal, prepare metadata, and prepare and upload data:

• Register for a synapse.org account

  1. Go to the Synapse website and click on the "Register Now" button.

  2. Enter a username and email address.

  3. You will receive an email from Synapse with instructions about completing registration.

• Join the MODEL-AD Team

  1. Once you have registered for a Synapse account, you can join the MODEL-AD Team by clicking on the "Teams" tab and searching for "MODEL-AD_DataUpload".

  2. Click on the "Join Team" button.

  3. Type an optional message and click on the "Send request" button.

• Contributing data to the portal

  1. Once you are a member of the MODEL-AD Team, you can contribute data to the portal by clicking on the "Contribute Data" button.

  2. You will be asked to provide some information about your data, such as the type of data, the size of the data, and the data format.

  3. You will also be asked to provide a citation for your data.

  4. Click on the "Submit Data" button.

What data and metadata can I contribute?

You can contribute any data and metadata that is relevant to your MODEL-AD research studies. This includes data on mouse models, protocols, and validated data.

What are the benefits of contributing data and metadata?

By contributing data and metadata, you can help to advance the field of Alzheimer's disease research. Your data and metadata will be made available to other researchers, which will help them to develop new treatments for Alzheimer's disease.

How do I contribute data and metadata?

• Contributing data to the portal

• Preparing Metadata

• Preparing and uploading Data

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How can I learn more?

If you have any questions about contributing data and metadata, please contact the MODEL-AD

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team.

• Who is involved in MODEL-AD Program?

  • The JAX.IU.Pitt Alzheimer's Disease Precision Models Center

  • UC Irvine AD Translational Center For Disease Model Resources

• MODEL-AD Studiesdata is available here: AD Knowledge Portal – MODEL-AD Data – searchable table of available data

• Experimental Mouse Models

• Data (including gene expression, immunoassay, proteomic, behavioral, and more)

• https://modeladexplorer.org/ – visual results explorer for AD-associated genes

Portal Resources

• AD Knowledge Portal

• https://help.adknowledgeportal.org/apd/About.1994096680.html

• https://help.adknowledgeportal.org/apd/Navigating-the-Portal.2062254157.html

• https://help.adknowledgeportal.org/apd/Accessing-Data.2137260765.html

  • Studies

  • Search for Data

  • Explore the Experimental Models used to target AD-genes

• Explore the the AD-related biomarker data in our https://modeladexplorer.org/

Thank you for your contribution!