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Sharing information about research tools is critical to help the neurofibromatosis (NF) research community discover tools available to enable and support their research. The NF Research Tools Central aims to support the development of a robust research toolkit and lower the barrier of entry to NF research. The database includes information on NF-associated animal models, cell lines, antibodies, and genetic reagents; details on tool characteristics and sourcing; as well as observational and experimental data.

Information available in the database has been generously contributed by the research community, as well as aggregated from publicly-available information across several research resource catalogs. Community contributions are encouraged at both the pre-publication and published stages, and may be annotated to indicate various stages of tool development and characterization. Contributors may provide details on tool availability, including any MTA requirements, instructions, and contact information to acquire a particular research tool.note

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Please note:Contributed information on research tools and associated observations will be made publicly available in the NF Research Tools Central. Contributions to the database are welcome at all stages of tool development and characterization. You are encouraged to speak with your institutional technology transfer office prior to sharing any proprietary information to confirm any restrictions on how and when information related to a particular tool may be shared publicly. Non-public information should not be submitted to the NF Research Tools Central without permission of the tool developer.

The database currently supports contributions of information about any animal models, cell lines, antibodies, genetic reagents, and biobanks that are related to the study of neurofibromatosis type 1, neurofibromatosis type 2, or schwannomatosis. If you are interested in contributing a research tool to the database, please visit How to Contribute a Tool

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We accept tools that are in any state of development, published or unpublished, as long as you envision sharing this tool to the public. We also encourage people researchers to submit tools in-development tools if they are seeking collaborators to help validate and improve the tool.

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Cell lines: immortalized cell lines or primary cell cultures that exist in a large enough quantity to be shared

Animal models: Genetically modified models of any species as well as well-characterized and shareable xenograft models

Antibodies: Any commercially available or self-distributed antibody for NF-relevant targets

Genetic reagents: Plasmids, guide RNAs, useful primers, or other genetic tools for studying NF

Biobanks: tissue Tissue or other biospecimen repositories with NF tumors or other NF-relevant biospecimens

Citing

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NF Research Tools Central

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To cite the NF Research Tools Central, please use the following citation:

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When a resource in our database is listed with an RRID, that indicates that some or all of the metadata was obtained from a Research Resource Identifier Initiative member. Licenses and references are described below; please consider citing these upstream repositories as necessary.

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