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These documents describe the prototype Neurofibromatosis Research Tools Database, which will be launching in early 2022. Check out a promo video on Loom: https://www.loom.com/share/ba520cc07aee4f4c888b8a8f269bc4f8

Articles:

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Data Model & Schema

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How to Contribute a Tool

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How to Contribute an Observation

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How to Update a Contribution

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The NF Research Tools Database aims to support the development of a robust research toolkit and lower the barrier of entry to neurofibromatosis (NF) research. The database includes NF-associated animal models, cell lines, antibodies, and genetic reagents and details on tool characteristics and sourcing, as well as observational and experimental data.

We allow contributions of information about any animal models, cell lines, antibodies, genetic reagents, and biobanks that are related to the study of neurofibromatosis type 1, neurofibromatosis type 2, or schwannomatosis.

Information has been generously contributed by the research community and has also been aggregated from several research resource catalogs. Please see below for information on who has provided information and important information about citing this and upstream resources:

Citing the NF Research Tools Database

Information in this database has also been curated by many data contributors, but has also been collected by other data repositories.

To cite the NF Research Tools Database, please use the following citation:

Clayton, Ashley, et al. “Centralizing Neurofibromatosis Experimental Tool Knowledge with the NF Research Tools Database.” MetaArXiv, 25 Jan. 2022. Web.

Acknowledgements

When a resource in our database is listed with an RRID, that indicates that some or all of the metadata was obtained from a Research Resource Identifier Initiative member. Licenses and references are described below; please consider citing these upstream repositories as necessary.

Research Resource Identification Initiative

Citation:

Bandrowski A, Brush M, Grethe JS, Haendel MA, Kennedy DN, Hill S, Hof PR, Martone ME, Pols M, Tan SC, Washington N, Zudilova-Seinstra E, Vasilevsky N; RINL Resource Identification Initiative. The Resource Identification Initiative: a cultural shift in publishing. Brain Behav. 2015 Dec 8;6(1):e00417. doi: 10.1002/brb3.417. PMID: 27110440; PMCID: PMC4834942.

AntibodyRegistry.org

Website: http://AntibodyRegistry.org

License: CC-BY-3.0

Citation:

Bandrowski,A. et al. (2011) An antibody registry for biological sciences. In, Front. Neuroinform. Conference Abstract: 4th INCF Congress of Neuroinformatics. doi: 10.3389/conf. fninf.

Cellosaurus

Website: https://web.expasy.org/cellosaurus/

License: CC-BY-4.0

Citation:

Bairoch A. The Cellosaurus, a cell line knowledge resource. J. Biomol. Tech. 29:25-38(2018). DOI: 10.7171/jbt.18-2902-002; PMID: 29805321; PMCID: PMC5945021

Mouse Genome Informatics

Website: http://www.informatics.jax.org/

License: CC-BY-4.0

Citation:

Bult CJ, Blake JA, Smith CL, Kadin JA, Richardson JE, the Mouse Genome Database Group. 2019. Mouse Genome Database (MGD) 2019. Nucleic Acids Res. 2019 Jan. 8;47 (D1): D801–D806.

Mammalian Phenotype Ontology

Website: http://www.informatics.jax.org/mgihome/other/Ontology_Licenses.shtml

License: CC-BY-4.0

Addgene

Website: http://Addgene.org

License: unknown

Citation:

Kamens J. (2015). The Addgene repository: an international nonprofit plasmid and data resource. Nucleic acids research, 43(Database issue), D1152–D1157. https://doi.org/10.1093/nar/gku893