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  • Grant Number

  • Contact PIs

  • Study Name (see naming conventions below)

  • Experimental models used

  • Assays performed

  • Data Formats

  • Number of individuals and biospecimens collected

Study Name Conventions

MODEL-AD study names should be formatted as follows.

Study type

Naming Format

Number of Strains

Primary Screen

Site_PrimaryScreen

  • Jax.IU.Pitt_PrimaryScreen

  • UCI_PrimaryScreen

Many

Strain Validation

Site_StrainValidation

  • Jax.IU.Pitt_StrainValidation

  • UCI_StrainValidation

Many

Deep Phenotyping

Site_Model

  • Jax.IU.Pitt_APOE4_Trem2

  • UCI_5XFAD

Many

Pharmacokinetic

Site_Model_Drug

  • Jax.IU.Pitt_5XFAD_Verubecestat

One

Pilot Studies

  • Microbiome

  • Proteomics

  • Metabolomics

Site_StudyType_Pilot

Examples:

  • Jax.IU.Pitt.Proteomics_Metabolomics_Pilot

Many

Study Organization

File Structure

Studies are organized in Synapse with a directory schema similar to this:

  • Study_Name/

    • Data/

      • Assay_a/

      • Assay_b/

    • Metadata/

    • Staging/ (Note: Files will initially be uploaded to staging locations)

      • Assay_*/

File naming

File names should be concise, descriptive, and unique across the entire study. We must be able to distinguish between each file as if there were all in one directory.

See general file naming recommendations from the Princeton U Library.

Study Documentation

Each study will need a Study Description, Methods Description, and Acknowledgment Statement. The Documentation Submission Form includes some templates for these documents and instructions about submitting the documents.

Study Description

MODEL-AD specific templates are being drafted and will be made available on Synapse (see Study, Acknowledgment, and Methods). Each study should be accompanied by a brief study description that includes the species, genetic background, a link to the Jax Datasheet (if available) or a description of how the animals were created.

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Methods Description

Each assay should include a brief description of the procedures, data collection, and analytical methods. This is a good opportunity to provide useful details that may not be included in the manuscript.

Acknowledgment Statement

Every MODEL-AD study should include the following acknowledgment:

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