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MODEL-AD data and metadata are organized by site and study. Studies are divided into directories by assay type, metadata, as well as a staging directory for data that has not yet been released.
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Each study should be accompanied by a brief study description that includes the species, genetic background, a link to the Jax Datasheet (if available) or a description of how the animals were created.
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Study and file naming conventions
Study name abbreviation
Descriptive study name
Only include animal model
Assay Description
Each assay assessment should be accompanied by a short description that includes specimen processingbrief description with information about the assessment procedures, data generation , and data processing, as applicable – something akin to and analytical methods. This information is often described in the Materials and Methods section of a manuscript. This is a good opportunity to clarify or provide additional detail that may not be included in the peer-reviewed manuscript.
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File naming conventions
Assay-specific examples. Need a list of most common assays.
RNA sequencing
Behavioral
Frailty
Open field
Acknowledgement Statement
All MODEL-AD studies should include the following acknowledgment:
The results published here are in whole or in part based on data obtained from the AD Knowledge Portal ( https://adknowledgeportal.synapse.org/ ). The IU/JAX/UCI MODEL-AD Center was established with funding from The National Institute on Aging (U54 AG054345-01 and AG054349). Aging studies are also supported by the Nathan Shock Center of Excellence in the Basic Biology of Aging (NIH P30 AG0380770).
Uploading Study and Assay Descriptions
These descriptions can be submitted via the Data Validator by selecting the ‘Documentation’ tab on the left side of the window. At present, you can’t see files after you’ve uploaded them. The data curation team will always look at file versions and date/time stamps and take the most recent version of the file, so if in doubt, please feel free to upload a new version.